Salt Nicotine or nicotine salts are made differently than regular e-liquid. This nicotine is very effective to help aid cigarette smokers in ditching the habit. Due to the higher nicotine content, nicotine salts more closely resemble the effects of smoking a cigarette and will help in curbing the craving. Nicotine salts are only to be used in Pod Devices, NOT SUB OHM. Nicotine Salts contain high levels of nicotine that could be harmful to you and your vaporizer if used in a sub-ohm tank.